Researchers at the University of California Davis have determined that a synthetic analog to cannabidiol can be effective for treating seizures in lab rats. Results of the research led by Mark Mascal, a professor in the UC Davis Department of Chemistry in collaboration with the University of Reading, U.K., were published last week by the journal Scientific Reports.
Researchers compared the effectiveness of herbal CBD and a synthetic version of CBD known as 8,9-Dihydrocannabidiol (H2CBD) in treating induced seizures in lab rats. They determined that the two compounds were equally effective in reducing both the frequency and severity of seizures.
Mascal said in a university press release that his lab has developed a process to produce H2CBD easily and inexpensively using commercially available chemicals. The manmade version of the drug has several advantages over its naturally derived counterpart, according to Mascal.
“It’s a much safer drug than CBD, with no abuse potential and doesn’t require the cultivation of hemp,” he said.
Hemp cultivation for CBD takes up land that could be used for other agricultural uses, including the cultivation of other varieties of hemp that can be used to produce fiber, grain, or oilseed. H2CBD can be produced more economically